TB Clip January 2022 article image

편집자 한마디!

국내외 결핵(TB)뉴스

학술연구자료

2022년 임인년, 더 행복하고 더 사랑하고 더 감사하는 한해 되시길 바랍니다.
놀랍게도 한경의 신춘문예에 다제내성 폐결핵 걸린 작가의 자전적 경험을 녹여낸 ‘방학’이라는 작품이 소설부분 당선작으로 선정되었습니다.
작가의 인터뷰에 의하면 폐결핵에 걸려 10년 동안 약이 하나도 안 들어 정말 죽음을 앞두고 있다가, 소설처럼 신약 임상시험에 참가하여 살아나게 되었다고 하는데, delamanid를 복약한 것 같아 제 어깨가 으쓱했습니다. 먼저 역경을 딛고 신춘문예에 당선되신 최설 소설가에게 축하 드리며, 다른 환자에게도 힘이 될 것 같아 소개해 보았습니다.

The WHO’s Global TB Programme Director Dr Tereza Kasaeva issues a review of 2021 – the highs and lows.

The Global Laboratory Initiative, with its secretariat at the World Health Organization Global TB Program, released a Planning and budgeting tool for TB and drug-resistant TB testing facilitating systematic calculation of the quantities and costs of products for countries planning to order diagnostic products and laboratory supplies from the Global Drug Facility Catalog.

The Stop TB Partnership announced the theme for this year’s World TB Day: Invest to End TB. Save Lives World leaders have only limited time until December 2022 to keep the promises made to their citizens and nations at the 2018 UN High-Level Meeting on TB. World TB Day is observed every year on 24 March to build public awareness about the global TB epidemic and efforts to eliminate the disease.

PEPFAR Watch brings together activists ahead of the Country Operational Plan planning process to develop priority recommendations and community demands for the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR). On 9 February 2022, PEPFAR Watch will host a webinar to discuss interventions for AIDS/advanced HIV disease including TB and cryptococcal meningitis. To register for the webinar, click here.

TB Alliance announced that it has received funding from the U.S. Agency for International Development (USAID) to jumpstart the search for new TB treatments, optimize current treatments, and strengthen health systems in high TB burden countries. The funding of up to US$30 million will be administered over a period of 5 years. here.

The Indian Ministry of Health in its revised Clinical Guidance for Management of Adult COVID-19 Patients added active TB as a high-risk factor that can potentially cause severe disease and even mortality in COVID-19 patients. The Ministry underlined the need for COVID-19 patients to undergo tests for TB and other conditions if their cough persists for more than 2-3 weeks. Source: Jagran Josh

Global funding for TB research totaled 915 million US dollars in 2020 – less than half the goal of 2 billion US dollars set forth by participating country governments at the 2018 United Nations High-Level Meeting on TB. Source: Africa.com

In response to the increase in rates of COVID-19 infection, the 6th Global Forum on TB Vaccines will be convened as a fully virtual event. To facilitate participation, it will now take place over four days on 22-25 February 2022. Applications for registration support are being accepted through 31 January 2022.

Delamanid is referred to in this opinion piece, in which it’s argued India is using TB diagnostic tools that too often are out-dated and ineffective. Delamanid is referred to in the context of new drugs available to treat TB. India is said to account for one third of global TB deaths.

Russia requires that anyone staying for more than 90 days be checked for TB, drug use and sexually-transmitted diseases.

Amazon Web Services is investing in a medical imaging technology company by supporting the hosting of cloud-based TB screening pilots in India. The pilot will allow for X-ray images to be sent to a virtual cloud where they can be processed by clinical and artificial intelligence partners. The aim is to speed up research and innovation that will advance understanding and detection of infectious diseases.

A new spin-off company from the University of Manchester, UK, called TaBrix, is working with the TB Alliance to create new treatments for drug-resistant TB.

Johnson & Johnson joined the national TB programmes of Indonesia, the Philippines, Thailand and Vietnam in hosting an Asia-Pacific TB forum. The two-day event identified several actions, including forging more public-private partnerships and addressing TB stigma, as part of the goal for ending TB.

Artificial Intelligence has helped to reduce diagnostic mistakes and helped to detect TB early improving treatments for patients, says a leading doctor in Vietnam.

A health district in Mumbai, India, finds recruiting TB survivors to counsel existing patients with the disease is reducing the number of drop-outs during treatment courses and increasing recovery rates.

A Mumbai health district is screening family members of TB patients in a bid to halve the city’s burden of the disease.

Here’s the Treatment Action Group (TAG) December 2021 update – referring to TAG achievements tackling TB during the year.

World TB Day theme for 2022 will be ‘Invest to end TB. Save Lives’ – as revealed in the Stop TB end of year message.

According to results of a cluster-randomized study published in The New England Journal of Medicine, a multicomponent diagnostic strategy was found to increase the number of patients being tested, diagnosed, and treated for confirmed TB infection.

Researchers reported that overseas culture-based TB screening in U.S.-bound immigrants and refugees substantially reduced the importation of multidrug-resistant TB into the U.S.

At the beginning of the pandemic it was suggested that countries with Bacillus Calmette-Guérin (BCG) vaccination programs could be associated with a reduced number and/or severity of COVID-19 cases. A new study suggested strategy to ‘complement and extend’ the protection offered by existing COVID-19 vaccines by using BCG vaccination.

A new study, using computational simulations, showed the potential role of a particular group of cells called neutrophils in the immune response to TB infection.

The rate of TB in London, UK, has not reduced during the COVID-19 pandemic. This might be surprising given that TB is airborne, and suggests important lessons about the transmission and treatment of the disease. Read the full analysis in The Lancet Respiratory Medicine.

A common framework that standardizes health impact across diseases and their interventions can aid in identifying current shortcomings on a global scale. The Global Health Impact Index model calculated the impact of drugs used to treat diseases affecting many impoverished people around the world: TB, HIV/AIDS, malaria, and several neglected tropical diseases.

Resist-TB is flagging this paper on its website; Nature publishes research identifying markers of future antibiotic resistance which could enable targeted therapy to prevent resistance emergence in Mtb and other pathogens.

Researchers in the US believe they have identified an enzyme which if targeted will tackle Mtb.

An academic who has spent years studying the spread of TB in Brazilian prisons finds those serving jail terms are as much as 30 times more likely to have the disease when compared with wider society.

A study undertaken among MDR-TB patients in Ethiopia suggests a levofloxacin-based regimen has better treatment success than moxifloacin-based approach.

Research conducted in China identifies cut-off points in treatment delay for poor outcomes and death among TB patients. This study also flags that TB diagnosis skills among community level health workers needs to be improved.

Research in The Lancet on TB in the Philippines argues that as much as screening, diagnosis and treatment are important, the disease will only be ended when socio-economic conditions of the poor and vulnerable are addressed.

The International Union Against Tuberculosis and Lung Disease released the January 2022 issue of the International Journal of Tuberculosis and Lung Disease (IJTLD). It predominantly includes TB-related research publications.

Public Health Action is the free access, online journal of The International Union Against Tuberculosis and Lung Disease. The journal focuses on TB, lung health, non-communicable diseases and related public health issues. The December 2021 issue is available here.

RESIST-TB released its December 2021 newsletter with the latest research publications on drug-resistant TB.